Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ WNK Signaling Inhibitor, Compound B
A cell-permeable compound that targets the conserved C-terminal domain of SPAK and OSR1 via reversible binding (Kd = 20 μM; rat SPAK-CCT452-553 GST fusion).
MilliporeSigma™ Calbiochem™ JAK2 Inhibitor IX, WP1193
A cell-permeable tyrphostin WP1130 (Cat
Novus Biologicals™ Camptothecin Inhibitor
Low molecular weight, organic compound that may help regulate biological process.
MilliporeSigma™ Calbiochem™ Ifenprodil Hemitartrate
A partial non-competitive antagonist highly selective for GluN1/N2B subtype NMDA receptors (IC50
MilliporeSigma™ Calbiochem™ PPM1D Phosphatase Inhibitor
The PPM1D Phosphatase Inhibitor, also referenced under CAS 1087-07-6, controls the biological activity of PPM1D Phosphatase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Bethanechol Chloride
Bethanechol Chloride is an agonist selective for Muscarinic Acetylcholine Receptors with no effect on nicotinic receptors.
MilliporeSigma™ Calbiochem™ MMP/TACE Substrate, FS-6
The widely used MMP substrate FS-1 is modified by an N-terminal lysine elongation to produce a broad-spectrum MMP and TACE substrate that displays improved water solubility and substrate sensitivities.
MilliporeSigma™ Calbiochem™ 5-Azacytidine
A cell-permeable ribonucleoside analog of cytidine that is reported to readily incorporate into RNA and DNA, and inhibit protein synthesis
MilliporeSigma™ Calbiochem™ InhibitorSelect™ FGF Signaling Pathway Inhibitor Panel
A panel containing 14 potent, selective, reversible and cell-permeable inhibitors useful for the study of multiple signaling pathways activated by FGF: 1 mg of Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 (Cat
MilliporeSigma™ Calbiochem™ Caspase Inhibitor, Negative Control
The Caspase Inhibitor, Negative Control, also referenced under CAS 105637-38-5, controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ A-803467
A voltage gated sodium channel type 1.8 (Nav1.8) pore blocker. Potently blocks tetrodotoxin-resistant currents (IC50) = 140 nM).
MilliporeSigma™ Calbiochem™ S1P1 Receptor Agonist, SEW2871
The S1P1 Receptor Agonist, SEW2871, controls the biological activity of S1P1 Receptor. This small molecule/inhibitor is primarily used for Activators/Inducers applications.
MilliporeSigma™ Calbiochem™ EGF/FGF/PDGF Receptor Tyrosine Kinase Inhibitor
The EGF/FGF/PDGF Receptor Tyrosine Kinase Inhibitor controls the biological activity of EGF/FGF/PDGF Receptor Tyrosine Kinase. Primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ 7α, 25-dihydroxycholesterol
A highly potent and specific oxysterol EBI2 (GPR183) agonist with a kd of 450 pM in a saturation binding analysis, and activates EBI2 (EC50 140 pM compared wit